Lipidation status of single membrane-associated ATG8 proteins

ATG8 are core autophagy proteins, the lipidated forms of which decorate double-membraned autophagosomes, as well single-membraned organelles such endolysosomes. Recent studies from Florey and Münz laboratories delineate status single membrane-associated proteins by indicating that their membrane anchoring can involve phosphatidylserine conjugation stabilization depends on ATG4 protease inhibition.